Iranian hackers broke into the address by Supreme Leader Ayatollah Khamenei on Saturday with the message, “The blood of our youth is dripping from your fingers.”
A second message said, “Rise up and join us!”
Photos of Mahsa Amini flashed across the television screen.
Protests broke out in Iran following the death of 22-year-old Mahsa Amini, who died in custody on September after police detained her because her hijab was not tight enough.
The Iran Human Rights Group reported 92 people have been killed, 41 just on Friday.
Iran’s semi-official Fars news agency admitted last week that “around 60” people had died.
Video has been released of protesters being gunned down by Iranian police.